CVS

CVS is a well-known drug store located in National City, California, situated at 1201 E Plaza Blvd. This location serves the local community as one of the area's accessible pharmacy and retail destinations, offering a range of health, wellness, and everyday essentials for residents and visitors alike.

One of the standout features of this CVS location in National City is its 24-hour availability. For those who find themselves in need of medication, personal care items, or quick grocery pickups at odd hours, this store remains open around the clock. Customers have noted that it is the only 24-hour CVS in the vicinity of San Diego, making it a particularly valuable resource for late-night or early-morning needs. Whether you are returning from a long trip, dealing with an unexpected health concern, or simply prefer shopping during quieter hours, this location accommodates a variety of schedules.

The store is generally described as clean and well-stocked, with shelves regularly maintained and organized. Customers have appreciated that even during nighttime hours, the staff makes an effort to keep the store in good order and assist those who walk through the doors. The product selection includes pharmacy services, over-the-counter medications, household goods, snacks, beverages, and personal care items — covering the essentials one would expect from a trusted national drug store chain.

Customer experiences at this CVS in National City are varied, as reflected in its 3.3-star rating from over 340 reviews. Some shoppers have praised the night staff for being willing to help with extra care and maintaining a family-friendly atmosphere. Others have expressed frustration with certain pharmacy interactions, including issues related to prescription processing and wait times at the pharmacy counter. It is worth noting that experiences can differ depending on the time of visit and the specific staff members on duty, so patience and clear communication with pharmacy personnel can go a long way toward a smoother experience.

Overall, CVS in National City, CA serves as a convenient and accessible option for those seeking a reliable drug store in the area — especially when other nearby locations are closed. Its 24-hour schedule, central location on E Plaza Blvd, and broad product range make it a practical stop for both planned errands and urgent needs. Visitors are encouraged to call ahead for specific pharmacy questions or to verify prescription details to help ensure the best possible experience upon arrival.